A powerful earthquake jolted Türkiye’s northwestern Duzce province early Wednesday, leaving a total of 46 people injured in the region, including in Istanbul, according to the Disaster and Emergency Management Authority (AFAD).

A total of 37 people were injured in Duzce, where the quake’s epicenter was located, while other injuries were reported in Istanbul, Sakarya, Bolu, and Zonguldak provinces, AFAD said.

Interior Minister Suleyman Soylu, who arrived in Duzce immediately after the quake, said there are no fatalities.

AFAD said a 5.9 magnitude earthquake centered in Golyaka District struck at 4.08 a.m. (0108GMT).

The quake occurred at a depth of 6.81 kilometers (4.2 miles).

It was also felt in Istanbul and other provinces, including northwestern Bolu, Sakarya, Kocaeli, Bursa, Bilecik, and western Izmir and Kutahya provinces, as well as the capital Ankara.

Following the quake, a total of 74 aftershocks were recorded. Power cuts are being imposed in the region as a precautionary measure, announced AFAD.

Duzce Governor Cevdet Atay announced that schools will be closed Wednesday due to the earthquake.

In 1999, Duzce province was hit by a 7.2 magnitude earthquake which lasted 30 seconds, killing 710 people and injuring 2,679, AA reports.