The Body Shop will close 75 shops in the UK over the coming weeks and cut 489 jobs, according to the firm overseeing its restructuring.
It means that, combined with cost-cutting at the company's head office, between 750 and 800 people will be made redundant.
However, The Body Shop will keep 116 UK stores open.
The UK arm of the global beauty chain was put into administration earlier this month.
Shops will be closed over the next four to six weeks. FRP Advisory, which is managing the restructuring, said it would "support all impacted staff with claims to the Redundancy Payments Service".
"In taking swift action to right-size The Body Shop UK store portfolio, we have stabilised the business," said FRP Advisory's Tony Wright.
"We remain fully focused on exploring all options to take the business forward."
Source: BBC